Nucleic Acid Extraction System And Purification Market Size

Type Insights

The RNA isolation and purification segment dominated the market for nucleic acid isolation and purification and accounted for the largest revenue share of 53.6% in 2020 owing to the increasing application in COVID-19 diagnostics and rise in use of purified mRNA for the construction of the cDNA library. These libraries have various applications such as gene expression profiling, sequencing, and clinical diagnostics. Moreover, the availability of a broad range of kits for extraction and processing of viral and bacterial RNA is further contributing to segment growth.

DNA isolation and purification is expected to witness lucrative growth of 13.5% during the forecast period owing to its increasing application in gene expression profiling. In addition, pharmaceutical and biotechnology companies are undertaking various strategic initiatives such as the launch of new products for efficiently carrying out nucleic acid isolation steps.

Viral DNA extraction and purification is increasingly gaining attention for their therapeutic and diagnostic applications. For instance, they are used as vectors for gene therapy and nanobiological weapons for fighting other viruses. The utilization of viral DNA in the market is henceforth gaining momentum through the coming years.

Method Insights

The magnetic beads segment dominated the market for nucleic acid isolation and purification and accounted for the largest revenue share of 37.9% in 2020 and is expected to continue the trend in the coming years. The growing adoption of magnetic beads is owing to the advantage that it provides researchers and scientists with improved assay performance and better isolation and purification of DNA and RNA.

In recent years, functionalized magnetic beads have been used along with suitable buffer systems for rapid and efficient extraction. This method reduces the requirement of centrifugation that usually results in the breaking of nucleic acids. Hence, such a positive aspect of this technology provides automated extraction with minimal requirement of centrifugation for nucleic acid isolation steps.

Column-based techniques are expected to witness substantial CAGR through the forecast period. Silica columns are extensively preferred for obtaining higher quality nucleic acids in a short time. In addition, these techniques can be incorporated in microchips and spin columns that have several advantages such as cost-effectivity, fast organic extraction, and compatibility with automated instruments. Hence, such methods are widely adopted in nucleic acid isolation methods.